Herpesvirus saimiri (ATCC® VR-1414)

Classification: Herpesviridae, Rhadinovirus  /  Product Format: frozen

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Classification Herpesviridae, Rhadinovirus
Agent Herpesvirus saimiri
Strain C-488 (US)
Common Name Herpesvirus saimiri
Biosafety Level 2
Product Format frozen
Storage Conditions -70°C or colder
Comments Lower passage of strain is also available as ATCC® VR-1396™, which requires a USDA permit due to culture containing FBS of Guatemalan origin.
Both strains transform human T lymphocytes to antigen- and mitogen-independent, but IL-2 dependent for stable growth.
For methods of preparation see: Fickenscher H. and B. Fleckenstein, 1994. in: Methods in Molecular Genetics. (Ed.) K. W. Adolph, 4: 345-362. Academic Press San Diego.
Effect on Host
CPE (foci of detached cells bordered by rounded enlarged cells)
Recommended Host
OMK cells (ATCC® CRL-1556™)
Growth Conditions

Incubation:  3 to 20 days at 37°C

Effect on Host
CPE (foci of detached cells bordered by rounded enlarged cells)
Name of Depositor H Fickenscher
Special Collection NCRR Contract
Source Derived from ATCC® VR-1396™, which came from the blood lymphocytes of a squirrel monkey (Saimiri sciureus) in New England
References

Biesinger B, et al. The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype. Virology 176: 505-514, 1990. PubMed: 2161148

Desrosiers RC, Falk LA. Herpesvirus saimiri strain variability. J. Virol. 43: 352-356, 1982. PubMed: 6287011

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