Herpesvirus saimiri (ATCC® VR-1414)

Classification: Herpesviridae, Rhadinovirus  /  Product Format: frozen

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Classification Herpesviridae, Rhadinovirus
Agent Herpesvirus saimiri
Strain C-488 (US)
Common Name Herpesvirus saimiri
Biosafety Level 2

Biosafety  classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions -70°C or colder
Comments Lower passage of strain is also available as ATCC® VR-1396™, which requires a USDA permit due to culture containing FBS of Guatemalan origin.
Both strains transform human T lymphocytes to antigen- and mitogen-independent, but IL-2 dependent for stable growth.
For methods of preparation see: Fickenscher H. and B. Fleckenstein, 1994. in: Methods in Molecular Genetics. (Ed.) K. W. Adolph, 4: 345-362. Academic Press San Diego.
Effect on Host
CPE (foci of detached cells bordered by rounded enlarged cells)
Recommended Host
OMK cells (ATCC® CRL-1556™)
Growth Conditions

Incubation:  3 to 20 days at 37°C

Effect on Host
CPE (foci of detached cells bordered by rounded enlarged cells)
Name of Depositor H Fickenscher
Special Collection NCRR Contract
Source Derived from ATCC® VR-1396™, which came from the blood lymphocytes of a squirrel monkey (Saimiri sciureus) in New England
References

Biesinger B, et al. The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype. Virology 176: 505-514, 1990. PubMed: 2161148

Desrosiers RC, Falk LA. Herpesvirus saimiri strain variability. J. Virol. 43: 352-356, 1982. PubMed: 6287011

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