Xanthophyllomyces dendrorhous Golubev (ATCC® 24202)

Strain Designations: UCD 67-210 [ATCC 96587, CBS 5905, CCRC 21346, CCY 77-1-1, DSM 5626, IFO 10129, IGC 4172, NCYC 874, NRRL Y-10921]  /  Product Format: freeze-dried

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Deposited As Phaffia rhodozyma Miller et al.
Strain Designations UCD 67-210 [ATCC 96587, CBS 5905, CCRC 21346, CCY 77-1-1, DSM 5626, IFO 10129, IGC 4172, NCYC 874, NRRL Y-10921]
Synonym Phaffia rhodozyma Miller et al.
Produces astaxanthin
Produces carotenoids
Produces glycoproteins
Increased production of carotinoids and trans-astaxanthin by addition of mevalonic acid
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain yes (type strain of Phaffia rhodozyma)
Preceptrol® no
Sequenced Data
D1D2 region of the 26S ribosomal RNA gene


Name of Depositor HJ Phaff
Fagus crenata, Kyoto, Japan
Cross References

Nucleotide (GenBank) : AF139634 nucleotide sequence of intergenic spacer

Nucleotide (GenBank) : AF189871 26S ribosomal RNA gene, partial sequence

Nucleotide (GenBank) : AF139629 nucleotide sequence of internal transcribed spacer


Johnson EA, et al. Processes for in vivo production of astaxanthin and Phaffia rhodozyma yeast of enhanced astaxanthin content. US Patent 5,356,809 dated Oct 18 1994

Golubev WI. Perfect state of Rhodomyces dendrorhous (Phaffia rhodozyma). Yeast 11: 101-110, 1995. PubMed: 7732720

Miller MW, et al. Phaffia, a new yeast genus in the Deuteromycotina (Blastomycetes). Int. J. Syst. Bacteriol. 26: 286-291, 1976.

. . Biotechnol. Lett. 17: 575-578, 1995.

Hayman GT, et al. Production of carotenoids by Phaffia rhodozyma grown on media composed of corn wet-milling co-products. J. Ind. Microbiol. 14: 389-395, 1995.

Tilser I, et al. Effect of supplementation of University of Wisconsin solution with glycoproteins from psychrophilic strains of yeast on hypothermic liver storage of rats. Cryobiology 33: 347-353, 1996. PubMed: 8689892

Breierova E. Cryoprotection of psychrophilic yeast species- by the use of additives with croprotective media. Cryo-Lett. 15: 191-197, 1994.

Fell JW, Blatt GM. Separation of strains of the yeasts Xanthophyllomyces dendrorhous and Phaffia rhodozyma based on rDNA IGS and ITS sequence analysis. J. Ind. Microbiol. Biotechnol. 23: 677-681, 1999. PubMed: 10455500

Fell JW, et al. Biodiversity and systematics of basidiomycetous yeasts as determined by large-subunit rDNA D1/D2 domain sequence analysis. Int. J. Syst. Evol. Microbiol. 50: 1351-1371, 2000. PubMed: 10843082

Calo P, et al. Mevalonic acid increases trans-astaxanthin and carotenoid biosynthesis in Phaffia rhodozyma. Biotechnol Lett 17: 575-578, 1995.

David-Palma M, Libkind D, Sampaio JP. Global distribution, diversity hot spots and niche transitions of an astaxanthin-producing eukaryotic microbe. Mol Ecol 23: 921-932, 2014. PubMed: 24372735

Hara KY, et al. Evaluation and screening of efficient promoters to improve astaxanthin production in Xanthophyllomyces dendrorhous. Appl Microbiol Biotechnol 98: 6787-6793, 2014. PubMed: 24737060

Loto I, et al. Enhancement of carotenoid production by disrupting the C22-sterol desaturase gene (CYP61) in Xanthophyllomyces dendrorhous. BMC Microbiol 12: 235, 2012. PubMed: 23075035

Linde D, et al. Molecular and biochemical characterization of a beta-fructofuranosidase from Xanthophyllomyces dendrorhous. Appl Environ Microbiol 75: 1065-1073, 2009. PubMed: 19088319

Libkind D, et al. Biogeography, host specificity, and molecular phylogeny of the basidiomycetous yeast Phaffia rhodozyma and its sexual form, Xanthophyllomyces dendrorhous. Appl Environ Microbiol 73: 1120-1125, 2007. PubMed: 17189439

Fell JW, et al. Molecular diversity and intragenomic variability in the yeast genus Xanthophyllomyces: the origin of Phaffia rhodozyma? FEMS Yeast Res 7: 1399-1408, 2007. PubMed: 17825066

type strain of Phaffia rhodozyma

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation