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26032 ^™

Histoplasma capsulatum Darling (ATCC^® 26032^™)

Alternate State: Ajellomyces capsulatus (Kwon-Chung) McGinnis et Katz, teleomorph / Strain Designations: G-217B / Product Format: frozen

Histoplasma capsulatum Darling ATCC^® 26032^™

frozen

For-Profit: $1,020.00 Non-Profit: $849.97

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Permits and Restrictions	View Permits
Deposited As	Histoplasma capsulatum Darling, anamorph
Strain Designations	G-217B
Alternate State	Ajellomyces capsulatus (Kwon-Chung) McGinnis et Katz, teleomorph
Application	Biomedical Research and Development Material Emerging infectious disease research Respiratory research
Biosafety Level	3 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format	frozen
Storage Conditions	Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Type Strain	no

Preceptrol®	no
Genome Sequenced Strain	Yes
Comments	iron acquisition mechanisms fungistasis neutralization of interleukin-12 yeast phase effect of continuous light and total darkness effect of pH differentiation of A and B phenotypes temperature-tolerant, high virulence; analysis of yps-3 gene Genome sequencing strain (The Genome Sequencing Center (GSC) at Washington University, USA).

Medium	ATCC^® Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions	Temperature: 25.0°C

Name of Depositor	MD Berliner
Chain of Custody	ATCC <<--MD Berliner<<--J.H. Seabury
Isolation	human, Louisiana
Cross References	Nucleotide (GenBank) : AF026268 M antigen gene, complete coding sequence Nucleotide (GenBank) : AF139985 catalase B (CATB) mRNA, complete coding sequence Nucleotide (GenBank) : AF189368 catalase isozyme A (CATA) mRNA, complete coding sequence Nucleotide (GenBank) : AF189369 catalase isozyme P (CATP) mRNA, complete coding sequence Nucleotide (GenBank) : L16844 Histoplasma capsulatum yeast phase specific (yps-3) gene, complete Nucleotide (GenBank) : L16845 Histoplasma capsulatum yeast phase specific (yps-3) mRNA, 3' end of Complete Genome (GenBank) : ABBT00000000 Ajellomyces capsulatus G217B, whole genome shotgun sequencing project
References	Keath EJ, Abidi FE. Molecular cloning and sequence analysis of yps-3, a yeast-phase-specific gene in the dimorphic fungal pathogen Histoplasma capsulatum. Microbiology 140: 759-767, 1994. PubMed: 8012597 Berliner MD, Biundo N Jr.. Effects of continuous light and total darkness on cultures of Histoplasma capsulatum. Sabouraudia 11: 48-51, 1973. PubMed: 4703465 Berliner MD. Histoplasma capsulatum: effects of pH on the yeast and mycelial phases in vitro. Sabouraudia 11: 267-270, 1973. PubMed: 4128915 Berliner MD. Histoplasma capsulatum: vital staining for the differentiation of the albino and brown phenotypes in vitro. Sabouraudia 11: 271-273, 1973. PubMed: 4128916 Weaver CH, et al. Localization of a yeast-phase-specific gene product to the cell wall in Histoplasma capsulatum. Infect. Immun. 64: 3048-3054, 1996. PubMed: 8757832 Timmerman MM, Woods JP. Ferric reduction is a potential iron acquisition mechanism for histoplasma capsulatum. Infect. Immun. 67: 6403-6408, 1999. PubMed: 10569756 Cain JA, Deepe GS Jr.. Interleukin-12 neutralization alters lung inflammation and leukocyte expression of CD80, CD86, and major histocompatibility complex class II in mice infected with Histoplasma capsulatum. Infect. Immun. 68: 2069-2076, 2000. PubMed: 10722603 Sorensen KN, et al. Murine models of blastomycosis, coccidioidomycosis, and histoplasmosis. Mycopathologia 146: 53-65, 1999. Newman SL, et al. Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum. Infect. Immun. 68: 5668-5672, 2000. PubMed: 10992469 Johnson CH, et al. Redundancey, phylogeny and differential expression of Histoplasma capsulatum catalases. Microbiology 148: 1129-1142, 2002. PubMed: 11932457 Magrini V, et al. Fosmid-Based Physical Mapping of the Histoplasma capsulatum Genome. Genome Res. 14: 1603-1609, 2004.

Permits	These permits may be required for shipping this product: Customer Acceptance of Responsibility, ATCC Form 62 required for distribution. Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation	Product Sheet Certificate of Analysis SDS