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MYA-826 ^™

Paracoccidioides brasiliensis (Splendore) Almeida, anamorph (ATCC^® MYA-826^™)

Strain Designations: Pb01 [01] / Product Format: frozen

Paracoccidioides brasiliensis (Splendore) Almeida, anamorph ATCC^® MYA-826^™

frozen

For-Profit: $354.00 Non-Profit: $294.99

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Permits and Restrictions	View Permits
Strain Designations	Pb01 [01]
Application	RAPD analysis Biomedical Research and Development Material
Biosafety Level	2 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format	frozen
Storage Conditions	Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Type Strain	no

Preceptrol®	no
Genome Sequenced Strain	Yes
Comments	highly virulent differential expression of proteins PbY20 (by yeast form) and PbM46 (by mycelial form) protein synthesis patterns effect of amphotericin B expression of gp43 differential expression of gene for heat shock protein, Hsp70 RAPD analysis Genome sequencing strain (University of Brasil, Brasil).

Medium	ATCC^® Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions	Temperature: 37.0°C

Name of Depositor	CM Soares
Special Collection	NCRR Contract
Chain of Custody	ATCC <<--CM Soares<<--M.R.R. Silva 01
Isolation	clinical isolate, Goiania, Brazil
Cross References	Nucleotide (GenBank) : AF148715 glucan synthase (FKS) gene, complete coding sequence Nucleotide (GenBank) : U91560 heat shock protein 70 gene, hsp70, complete coding sequence Complete Genome (GenBank) : ABKH00000000 Paracoccidioides brasiliensis Pb01, whole genome shotgun sequencing project
References	Pereira M, et al. Molecular cloning and characterization of a glucan synthase gene from the human pathogenic fungus Paracoccidioides brasiliensis. Yeast 16: 451-462, 2000. PubMed: 10705373 Cunha AF, et al. Identification, N-terminal region sequencing and similarity analysis of differentially expressed proteins in Paracoccidioides brasiliensis. Med. Mycol. 37: 115-121, 1999. PubMed: 10361267 Salem-Izacc SM, et al. Protein synthesis patterns of Paracoccidioides brasiliensis isolates in stage-specific forms and during cellular differentiation. J. Med. Vet. Mycol. 35: 205-211, 1997. Jesuino RS, et al. In vitro amphotericin B effects on growth, viability and dimorphism of Paracoccidioides brasiliensis: reversal of the treatment. Microbiol. Immunol. 41: 93-99, 1997. PubMed: 9087951 Mattar-Filho R, et al. Expression of glycoprotein gp43 in stage-specific forms and during dimorphic differentiation of Paraccidioides brasiliensis. J. Med. Vet. Mycol. 35: 341-345, 1997. da Silva SP, et al. Phase transition and stage-specific protein synthesis in the dimorphic fungus Paracoccidioides brasiliensis. Exp. Mycol. 18: 294-299, 1994. da Silva SP, et al. Differential expression of an hsp70 gene during transition from the mycelial to the infective yeast form of the human pathogenic fungus Paracoccidioides brasiliensis. Mol. Microbiol. 31: 1039-1050, 1999. PubMed: 10096073 Celia M Soares, personal communication Wang H, et al. A fungal phylogeny based on 82 complete genomes using the composition vector method. BMC Evol. Biol. 9: 195, 2009. PubMed: 19664262

Permits	These permits may be required for shipping this product: Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation	Product Sheet Certificate of Analysis SDS