Derivation
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The cell line designated Dubca (Dubai Camel) was originated in 1990 from a specimen taken from a fetus during the autopsy of the mother at the Veterinary Research Laboratory in Dubai, UAE.
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Virus Resistance
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parapox virus; canine adenovirus type 1 (CAV); Aleutian disease virus (ADV); influenza virus (A equi 1); ECBO virus, equine arteritis virus (EAV)
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Comments
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The cell line designated Dubca (Dubai Camel) was originated in 1990 from a specimen taken from a fetus during the autopsy of the mother at the Veterinary Research Laboratory in Dubai, UAE. Cells at passage 7 were transformed by infection with SV40 and the resulting cells were cloned in soft agar. SV40 large T-antigen is detected by Western blotting. The cell line is susceptible to infection with viruses of several different families. Orf, Newcastle disease virus (NDV) and Sindbis virus show an abortive infection with virus replicating only in the first passages. While some isolates of bovine viral diarrhea virus (BVDV) and border disease virus (BDV) could not be grown in Dubca cells other isolates could be propagated to a limited extent (only a few cells expressed viral antigen). The cells may be used for virus diagnosis and vaccine production.
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