Colon Cancer Panel 2, BRAF (ATCC^® TCP-1007^™)

SNU-C1, ATCC CRL-5972

SW48, ATCC CCL-231

RKO, ATCC CRL-2577

COLO 205, ATCC CCL-222

SW1417, ATCC CCL-238

LS411N, ATCC CRL-2159

NCI-H508, ATCC CCL-253

HT-29, ATCC HTB-38

Biological understanding of top genetic alterations across tumor types

Validation and characterization of potential cancer driver genes

Functional profiling and molecular profiling of subtype-specific cancer cell lines

Testing small molecules or biologics for cancer drug development

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

A panel of 8 colon cancer cell lines with varying degrees of genetic complexity. They have genomic mutations in one or more of the following genes according to the Sanger COSMIC database: BRAF, APC, CTNNB1, EGFR, FBXW7, NF1, PIK3CA, PIK3R1, SMAD4, and TP53.