Derivation
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Lymph node cells were fused with Sp2/0 mouse myeloma cells. Initial hybrids were refused with additional lymph node cells from the same animal and reselected.
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Genes Expressed
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immunoglobulin; monoclonal antibody; against bovine herpesvirus 1 (BHV-1)
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Cellular Products
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immunoglobulin; monoclonal antibody; against bovine herpesvirus 1 (BHV-1)
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Comments
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Animals were immunized with live BHV-1. Lymph node cells were fused with Sp2/0 mouse myeloma cells. Initial hybrids were refused with additional lymph node cells from the same animal and reselected. The antibody neutralizes BHV-1 and is protective against BHV-1 induced mortality in rabbits.
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