|
Components
|
SW1990, ATCC CRL-2172
SU.86.86, ATCC CRL-1837
BXPC-3, ATCC CRL-1687
Panc 10.05, ATCC CRL-2547
MIA-PaCa-2, ATCC CRL-1420
PANC-1, ATCC CRL-1469
|
|
Applications
|
Biological understanding of top genetic alterations in pancreatic cancer
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Biological understanding of top genetic alterations in leukemia
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development |
|
|
Biosafety Level
|
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
|
|
Comments
|
The Pancreatic Cancer p53 Hotspot Mutation Cell Panel is composed of six select adhesion cell lines derived from individuals with pancreatic cancer. The mutations have been sequenced and validated by ATCC. This panel includes p53 wild type cell lines as well as p53 mutant lines that carry hotspot mutations in one of the following codons: 220, 245, 248, 255 and 273.
|
|
Storage Conditions
|
liquid nitrogen vapor phase
|