Pancreatic Cancer p53 Hotspot Mutation Cell Panel (ATCC® TCP-2060)

Organism: Homo sapiens, human  / 

Organism Homo sapiens, human
Components

SW1990, ATCC CRL-2172

SU.86.86, ATCC CRL-1837

BXPC-3, ATCC CRL-1687

Panc 10.05, ATCC CRL-2547

MIA-PaCa-2, ATCC CRL-1420

PANC-1, ATCC CRL-1469

Applications

Biological understanding of top genetic alterations in pancreatic cancer
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development


Biological understanding of top genetic alterations in leukemia
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Biosafety Level 1
Comments

The Pancreatic Cancer p53 Hotspot Mutation Cell Panel is composed of six select adhesion cell lines derived from individuals with pancreatic cancer. The mutations have been sequenced and validated by ATCC. This panel includes p53 wild type cell lines as well as p53 mutant lines that carry hotspot mutations in one of the following codons: 220, 245, 248, 255 and 273.

Product Format frozen
Storage Conditions liquid nitrogen vapor phase