Dengue virus type 3 (ATCC® VR-1689)

Classification: Flaviviridae, Flavivirus  /  Product Format: frozen

Permits and Restrictions

View Permits

Classification Flaviviridae, Flavivirus
Agent Dengue virus type 3
Strain Monoclonal anti-Dengue virus type 3 E protein, clone E8 (produced in vitro)
Biosafety Level 1
Product Format frozen
Storage Conditions  -20°C or colder Repeated freeze-thaw cycles should be avoided
Comments
Antibody Class: IgG1κ
The B cell hybridoma was generated by the fusion of P3X63.Ag.8.6.5.3 BALB/c mouse myeloma cells with immunized mouse splenocytes. The clone E8 antibody is reported to bind to domain III in the envelope glycoprotein.
Name of Depositor MS Diamond, Washington University in St. Louis, School of Medicine
Source
Mouse monoclonal antibody prepared against the envelope glycoprotein of dengue virus type 3 was purified from clone E8 hybridoma supernatant by protein G affinity chromatography.
References

Balsitis SJ, et al. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6: e1000790, 2012. PubMed: 20168989

Rajamanonmari R, et al. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J. Gen. Virol. 90: 799-809, 2009. PubMed: 19264660

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation