Bovine herpesvirus 1 (ATCC® VR-2160)

Classification: Herpesviridae, Varicellovirus  /  Product Format: frozen
1 mL per vial

Classification Herpesviridae, Varicellovirus
Deposited As Infectious bovine rhinotracheitis virus
Agent Bovine herpesvirus 1
Strain beta GAL INV tk-
Common Name Infectious bovine rhinotracheitis virus, Bovine rhinotracheitis virus
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Isolation
Parental virus was ATCC VR-188, LA strain, from dairy cattle in California. An intermediate in the formation of beta-gal INV was VR-2006
Product Format frozen
1 mL per vial
Storage Conditions -70°C or colder
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Comments This strain is an Infectious bovine rhinotracheitis vaccine candidate. It is temperature-sensitive, and due to a 3 kb insertion of E. coli K12, beta-galactosidase in the tk gene is tk-negative.
Effect on Host
CPE
Recommended Host RAB-9 (ATCC CRL-1414)
Growth Conditions Temperature: 34.5°C
Incubation: 3-4 days
Cryopreservation
Storage temperature: -70C
Effect on Host
CPE
Name of Depositor S Kit, Baylor College of Medicine and NovaGene, Inc.
U.S. Patent
U.S. Patent Number
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Source Parental virus was ATCC VR-188 An intermediate in the formation of beta-galactosidase INV was ATCC VR-2006
Year of Origin 2006
References

Kit M, Kit S. Infectious bovine rhinotracheitis virus insertion mutants, vaccines containing same, and methods for the production of same. US Patent 5,601,816 dated Feb 11 1997

Madin SH, et al. Isolation of the infectious bovine rhinotracheitis virus. Science 124: 721-722, 1956. PubMed: 13371311