Certified Reference Materials (CRMs)

  • SRM Genomic DNA Standards for HER2 Measurements (ATCC® NIST-2373)

    ATCC® Number: NIST-2373

    Quantity: 100 µL of DNA solution per vial
    Applications: Used to assign ratios of the human epidermal growth factor 2 gene (HER2; the official gene symbol ERBB2) to unamplified reference genes. Measurements of the amplification (increased copies) of the HER2 gene in breast cancer samples are used as a biomarker for determining the classification for breast cancers

    For-Profit:   $1,473.00 Non-Profit:   $1,473.00

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    Product Format: 100 µL of DNA solution per vial
    Comments: SRM NIST-2373 consists of genomic DNA extracted from five breast cancer cell lines with different amounts of amplification of the HER2 gene. The five purified genomic DNAs were solubilized in a buffer consisting of 10 mmol/L tris(hydroxymethyl)aminomethane and 0.1 mmol/L ethylenediaminetetraacetic acid disodium salt (EDTA) pH 8.0 (TE–4). The five components are genomic DNA materials derived from human cell lines SK-BR-3, MDA-MB-231, MDA-MB-361, MDA-MB-453, and BT-474, labeled A, B, C, D, and E, respectively. A unit of SRM 2373 consists of five vials, one of each component, containing approximately 100 μL of DNA solution. Each of these vials is labeled and is sealed with a color-coded screw cap.

    See the NIST Certificate of Analysis for directions for use and quality control specifications. 

    Certificate of Analysis

    NIST SDS

  • NCI-H441 [H441] (ATCC® CRM-HTB-174)

    ATCC® Number: CRM-HTB-174

    Organism: Homo sapiens, human
    Cell Type: Epithelial Cell (Kras Crm)
    Tissue: Lung
    Disease Papillary Adenocarcinoma

    For-Profit:   $714.00 Non-Profit:   $535.50

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    Tissue: Lung
    Product Format: frozen
  • Acholeplasma laidlawii (Sabin) Edward and Freundt (ATCC® qCRM-23206D)

    ATCC® Number: qCRM-23206D

    Strain Designations: Genomic DNA from Acholeplasma laidlawii strain PG8 [NCTC 10116, PG8; A]
    Type Strain: yes
    Biosafety Level: 1

    For-Profit:   $490.00 Non-Profit:   $490.00

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    Biosafety Level: 1
    Product Format: frozen
    Specification range: 1x106 - 1x107 genome copies/µL
  • SRM PCR-Based DNA Profiling Standard (ATCC® NIST-2391c)

    ATCC® Number: NIST-2391c

    Storage: Store in the dark between 2°C to 8°C. DO NOT FREEZE.
    Applications: For use in the standardization of forensic and paternity quality assurance procedures for polymerase chain reaction (PCR)-based genetic testing, for instructional law enforcement or non-clinical research purposes, and for quality assurance when assigning values to in-house control materials. It is not intended for any human or animal clinical diagnostic use.

    For-Profit:   $1,119.00 Non-Profit:   $1,119.00

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    Comments: SRM NIST-2391c is composed of well-characterized human deoxyribonucleic acid (DNA) in two forms: genomic DNA (Components A through D) and DNA to be extracted from cells that have been spotted onto 903 paper (Component E) and FTA paper (Component F).

     

    Component Description Amount Concentration(a)
    A Anonymous single-source female genomic DNA in TE-4 buffer 50 μL 1.1 – 2.1 ng/μL
    B Anonymous single-source male genomic DNA in TE-4 buffer 50 μL 1.1 – 2.1 ng/μL
    C Anonymous single-source male genomic DNA in TE-4 buffer 50 μL 1.1 – 2.1 ng/μL
    D Mixed-source (Components A and C) genomic DNA in TE-4 buffer 50 μL 1.1 – 2.1 ng/μL
    E Anonymous single-source female cells spotted on 903 paper Two 6 mm punches 7.5 × 104 cells per punch
    F Anonymous single-source male cells spotted on FTA paper Two 6 mm punches 7.5 × 104 cells per punch

     

    See the NIST Certificate of Analysis for directions for use and quality control specifications. 

    Certificate of Analysis

    NIST SDS

     

  • MDA-MB-231 (ATCC® CRM-HTB-26)

    ATCC® Number: CRM-HTB-26

    Organism: Homo sapiens, human
    Cell Type: Epithelial
    Tissue: Mammary Gland/Breast; Derived From Metastatic Site: Pleural Effusion
    Disease Adenocarcinoma

    For-Profit:   $714.00 Non-Profit:   $535.50

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    Tissue: Mammary Gland/Breast; Derived From Metastatic Site: Pleural Effusion
    Product Format: frozen
  • Staphylococcus aureus subsp. aureus Rosenbach (ATCC® CRM-6538)

    ATCC® Number: CRM-6538

    Strain Designations: FDA 209
    Type Strain: no
    Biosafety Level: 2

    For-Profit:   $420.00 Non-Profit:   $315.00

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    Biosafety Level: 2
    Product Format: freeze-dried