Components
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Neo Jurkat, ATCC CRL-2898
BCL2 Jurkat, ATCC CRL-2899
BCL2 (S70A) Jurkat, ATCC CRL-2900
BCL2 (S87A) Jurkat, ATCC CRL-2901
BCL2 (AAA) Jurkat, ATCC CRL-2902
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Applications
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The Cell Death Pathway BCL-2 Family Cell Line Panels 1 & 2 are useful for the study of cell apoptosis signaling pathways, BCL-2 family member molecular mechanisms, and mitochondrial dysfunction.
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Biosafety Level
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2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
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Comments
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The Cell Death Pathway BCL-2 Family Cell Line Panel 1 is composed of five Jurkat leukemia cell lines that stably overexpress either wild-type BCL-2 or a mutant form of BCL-2. The BCL-2 mutations include phosphorylation site substitutions S70A, S87A, and a triple subsitution AAA (T69A, S70A, S87A). Mutations have been sequenced and validated by ATCC.
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Product Format
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frozen 5 cryopreserved cell lines
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Storage Conditions
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liquid nitrogen vapor phase
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