Components
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Applications
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Biological understanding of top genetic alterations across tumor types Validation and characterization of potential cancer driver genes Functional profiling and molecular profiling of subtype-specific cancer cell lines Testing small molecules or biologics for cancer drug development
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Biosafety Level
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1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
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Comments
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A panel of 5 bone cancer cell lines with varying degrees of genetic complexity. Four lines contain genomic mutations in one or more of the following genes according to the Sanger COSMIC database: CDKN2A, BRAF, TP53, RB1, and PTEN. One cell line without coding mutations serves as a control.
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Storage Conditions
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LN vapor (less than -130°C) only
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