Excellence in Research webinar series
Your trusted resource for the world’s largest and most diverse collection of human and animal cell lines, microorganisms, biological products, standards, and custom services announces the 2016 Excellence in Research webinar series. The series will showcase the implementation of leading technologies, the importance of standards, and the application of new ATCC products and services to advance your scientific research. The webinars will broadcast live for 30 to 45 minutes and will be followed by a 10 minute question and answer period. Register to join the webinar that best meets your schedule.
Finding your perfect match – evolving technologies for bacterial strain typing
Brian Cantwell, Ph.D., Scientist, ATCC
September 15, 2016
Abstract: Bacterial strains within the same species can show a wide range of genetic differences, from only a few nucleotides to large chromosomal variations. Identifying specific strains can provide important clues to antimicrobial resistance or virulence factors, and is central to epidemiological studies of disease outbreaks. In this webinar, we will look at the variety of typing information used to identify strains in the ATCC catalog. From traditional serological methods to various electrophoresis-based molecular methods and the latest applications of whole genome sequencing, we will discuss these technologies, their applications in current literature, and how ATCC is working to improve strain typing by providing quality control and reference materials.
- The amount and type of strain difference within a given species of bacteria can differ widely and has given rise to a variety of strain typing technologies
- Molecular methods have become predominant and have evolved from primarily electrophoresis-based methods, such as Pulse Field Gel Electrophoresis, to sequence-based methods, such as those based on one or more loci
- Whole genome sequencing offers great promise for future typing as it offers both high resolution and the power of examining many loci, but comes with challenges in terms of quality control and data management
Dr. Cantwell has been with ATCC for three years and is the Microbiology Scientist with the ATCC’s Central Accessioning Unit. He has a Ph.D. in Microbiology and has worked in the fields of bacterial pathogenesis, bacterial chemotaxis, microbial genetics, and biochemistry using both laboratory and bioinformatics approaches.
Register for this session 12:00 PM ET.
ATCC Quantitated Nucleic Acids – Empowering Molecular-based Assay Development
Fang Tian, Ph.D., Lead Scientist, ATCC Cell Systems
Cynthia Long, Product Line Business Manager, ATCC Microbiology Systems
September 22, 2016
Abstract: Molecular diagnostics are increasingly relied upon to direct appropriate therapies for the personalized treatment of cancer patients as well as to identify, track, and quantify pathogenic microorganisms. To ensure the reliability and reproducibility of these assays, authenticated controls with confirmed identity, stability, and functionality are required. In this presentation, we will discuss our growing portfolio of quantitative nucleic acids that have been purified or synthetically derived from characterized cell lines and microorganisms. With next-generation sequencing verified gene mutation allelic frequencies and virulence genes, as well as Droplet Digital™ PCR quantified absolute copy numbers, ATCC quantitative nucleic acids provide reliable and sustainable controls for oncology molecular diagnostic assays, infectious disease research, and quality control testing.
- Human genomic DNAs with known mutational allelic frequency and copy number variation are essential control materials for developing molecular diagnostic tests
- Quantitative microbial nucleic acids are critical for the development of assays designed for the detection and quantification of pathogenic strains
- ATCC quantitative nucleic acids are ideal for use in inclusivity/exclusivity testing, establishing limits of detection, and validating or comparing test methods
Dr. Fang Tian, Lead Scientist, head of the Translational Cell Biology Group for ATCC Cell Systems, has extensive experience in cell biology and molecular biology. She oversees human, animal cell lines and hybridomas, and product development in the Cell Biology General Collection at ATCC. Dr. Tian was a research fellow in Massachusetts General Hospital, Harvard Medical School. She conducted postdoctoral research at the Hillman Cancer Institute of UPMC.
Cynthia Long, Product Line Business Manager, ATCC Microbiology Systems, has comprehensive experience in the medical device space, biological sciences, and business development. At ATCC, she oversees the development of microbiological and molecular products that support assay development, quality control testing, and research on infectious diseases. Ms. Long has a bachelor’s degree in Microbiology from Miami University.
Register for this session 12:00 PM ET.
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