™ BT142 mut/- (Homozygous) cells have lost the wild-type IDH1 allele but retains the mutant allele. The loss of the wild-type allele has been reported in vivo
in patients and has been shown to be similar to phenotypically wild-type IDH, resulting in decreased 2-hydroxyglutarate production.
|Date Created||03/29/2013 01:08 PM
|Date Updated||03/27/2014 08:39 PM