ATCC Cell Line Land: Reference-Quality RNAseq Data from Credible ATCC Cell Lines Webinar

February 22, 2024, at 12:00 PM ET

Abstract

With the increasing adoption of cell lines set to replace traditional animal-based methods in biomedical research, there is an urgent need for standardized practices. Treating cells as fundamental reagents is imperative for designing reproducible assays. Recognizing this need, ATCC^® has expanded its cell line authentication program to meet current and future demands. Through our alliance with QIAGEN^® Digital Insights, ATCC^® has launched ATCC Cell Line Land. This digital platform provides comprehensive whole-transcriptome sequencing data for ATCC's authenticated human and mouse cell lines. The platform empowers researchers by visualizing gene expression patterns thereby enabling the selection of suitable cell line models for their specific research areas. The high-quality transcriptomic datasets generated through ATCC^® Cell Line Land offer invaluable molecular insights into different cell lines. This not only saves researchers time and resources related to cell line characterization but also enhances the selection of cell lines for preclinical studies. By advancing cell line characterization through high-throughput RNA-seq data and accompanying metadata, this platform enhances scientific rigor and contributes to reducing the risk of irreproducibility in research endeavors.

Key takeaways:

Treating cells as fundamental reagents is essential for designing reproducible assays.
Through our alliance with QIAGEN^® Digital Insights, ATCC^® has introduced a state-of-the-art digital platform that offers comprehensive whole-transcriptome sequencing data for ATCC's cell lines.
ATCC^® Cell Line Land supports numerous studies such as biomarker discovery, transcript identification, splice variant analysis, and mutation profiling.
These high-quality transcriptomic data streamline cell line characterization, aid in selecting appropriate cell lines for preclinical studies, and contribute to reducing the risk of irreproducibility in research.

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Presenter

Ajeet Singh, PhD

Senior Scientist, ATCC

Dr. Ajeet Singh is Senior Scientist at ATCC where he is focused on providing reference-grade whole transcriptome data that is authenticated, standard, and traceable to physical source materials available in ATCC’s biorepository. Prior to joining ATCC, Dr. Singh received his PhD in Agricultural Plant Pathology where he performed research focused on epidemiology and integrated management of plants pests and diseases. He then performed postdoctoral research at the National Institute of Environmental Health Sciences and subsequently worked as a Senior Staff Scientist at the National Cancer Institute. Dr. Singh has extensive experience in biomedical research with his research career expanding an array of interrelated disciplines exploring epigenetics, chromatin and gene expression in reproductive developmental toxicology, stem cell biology, and cancer.