Human adenovirus 41 (ATCC® VR-930)

Classification: Adenoviridae, Mastadenovirus, Human adenovirus F  /  Product Format: frozen 1 mL per vial

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Classification Adenoviridae, Mastadenovirus, Human adenovirus F
Deposited As Adenovirus type 41
Agent Human adenovirus 41
Strain Tak (73-3544)
Applications
Enteric Research
Biosafety Level 2
Product Format frozen 1 mL per vial
Storage Conditions -70°C or colder
Comments Good immunogen in rabbits. No two-way cross serum neutralization or HA with 37 prototypes. Related to strain Dugan (79-18025) by serum neutralization and HAI. HA at low titer in rat red blood cells. No HA in rhesus monkey or human O type red blood cells. GenBank: DQ315364.2.
Effect on Host
CPE, cell rounding, clumping, sloughing
Recommended Host
293 [HEK-293] (ATCC® CRL-1573™)
Growth Conditions Temperature: 37°C
Recommendations for Infection: Plate cells 24 hours prior to infection and infect when cultures are 80-90% confluent. Remove medium and inoculate with a small volume of virus (e.g. 1 mL per 25 cm2) diluted to provide an optimal MOI (e.g. 0.1). Adsorb 1-2 hours at 37°C in a humidified 5% CO2 atmosphere, rocking every 15 minutes to redistribute inoculum. End adsorption by adding virus growth medium.
Incubation: 2-7 days
Effect on Host
CPE, cell rounding, clumping, sloughing
Name of Depositor JC de Jong, National Institute for Public Health and the Environment, Netherlands
Special Collection ATCC
Source Feces from 14 month old with gastroenteritis, Netherlands, 1973
References

Brown M, et al. Diagnosis of fastidious enteric adenoviruses 40 and 41 in stool specimans. J. Clin. Microbiol. 20: 334-338, 1984. PubMed: 6490823

Hierholzer JC, et al. Evaluation of human adenoviruses 38, 39, 40, and 41 as new serotypes. Intervirology. 29: 1-10, 1988. PubMed: 3384629

Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904

de Jong JC, et al. Candidate adenoviruses 40 and 41: fastidious adenoviruses from human infant stool. J. Med. Virol. 11: 215-231, 1983. PubMed: 6306161

Ma Y, Mathews MB. Structure, function, and evolution of adenovirus-associated RNA: a phylogenetic approach. J. Virol. 70: 5083-5099, 1996. PubMed: 8764016

Cross References

Nucleotide (GenBank) : U52573 Human adenovirus type 41 virus-associated RNA pre-terminal protein (pTP) and 52,55K protein genes, partial cds.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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