Bovine herpesvirus 1 (ATCC® VR-2160)

Classification: Herpesviridae, Varicellovirus  /  Product Format: frozen
1 mL per vial

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Classification Herpesviridae, Varicellovirus
Deposited As Infectious bovine rhinotracheitis virus
Agent Bovine herpesvirus 1
Strain beta GAL INV tk-
Common Name Infectious bovine rhinotracheitis virus, Bovine rhinotracheitis virus
Biosafety Level 2

Biosafety  classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Parental virus was ATCC VR-188, LA strain, from dairy cattle in California. An intermediate in the formation of beta-gal INV was VR-2006
Product Format frozen
1 mL per vial
Storage Conditions -70°C or colder
Comments This strain is an Infectious bovine rhinotracheitis vaccine candidate. It is temperature-sensitive, and due to a 3 kb insertion of E. coli K12, beta-galactosidase in the tk gene is tk-negative.
Effect on Host
Recommended Host RAB-9 (ATCC CRL-1414)
Growth Conditions Temperature: 34.5°C
Incubation: 3-4 days
Storage temperature: -70C
Effect on Host
Name of Depositor S Kit, Baylor College of Medicine and NovaGene, Inc.
U.S. Patent Number
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished.
Source Parental virus was ATCC VR-188. An intermediate in the formation of beta-galactosidase INV was ATCC VR-2006.
Year of Origin 2006

Kit M, Kit S. Infectious bovine rhinotracheitis virus insertion mutants, vaccines containing same, and methods for the production of same. US Patent 5,601,816 dated Feb 11 1997

Madin SH, et al. Isolation of the infectious bovine rhinotracheitis virus. Science 124: 721-722, 1956. PubMed: 13371311

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customer Acceptance of Responsibility, ATCC Form 62 required for distribution.
  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
  • USDA APHIS VS 16-6 or 16-6A permit must be obtained and a copy of the permit must be sent to ATCC in advance of shipment. The Application Form VS 16-3 (Import controlled material import or transport organisms or vectors) must be submitted to USDA APHIS Veterinary Services to obtain the VS 16-6 or 16-6A permit.
Basic Documentation