Infectious Diseases -
Limit of Detection

Determining the detection limit is an essential part of assay development and design. Trust the leading provider of authenticated cultures and nucleic acids as your source for quantified reference standards.




The performance of culture- and molecular-based assays is often evaluated through the examination of sensitivity, specificity, and limit of detection (LOD). Depending on the assay, LOD is the minimum amount of target microorganisms or genome copies that can be reliably detected under optimal conditions. Accurate determination of LOD relies on the use of authenticated microbial or molecular controls with known concentrations.


For this reason, ATCC has expanded its portfolio of products and services to include:

  • Quantified microorganisms 
  • Native nucleic acids with known concentration
  • Synthetic nucleic acids with calculated genome copy number
  • Extraction and quantification services

These products are produced under ISO 9001:2008 certified and ISO/IEC 17025:2005 accredited processes, and are quantified using verified methods, so you can trust the accuracy of your results.


Use the links below to find the resources you need. Or, contact the ATCC Sales Team.

ATCC® Genuine Nucleics

ATCC® Genuine Nucleics encompass a large and diverse array of native, synthetic, and certified reference materials for use in establishing assay sensitivity and specificity.

 

Explore

Customized Solutions

Need an affordable solution to extractions, titering, and quantification? ATCC can help with customized services and solutions to meet your specific assay development needs.

  

Contact us

Mycoplasma Quality Control

Titered mycoplasma strains and quantitated nucleic acids for use in inclusivity/exclusivity testing, establishing limits of detection, and validating or comparing test methods.

 

Learn more