Cowpox virus (ATCC® VR-302)

Classification: Poxviridae, Orthopoxvirus  /  Product Format: frozen

Classification Poxviridae, Orthopoxvirus
Deposited As Cowpox virus, Orthopoxvirus
Agent Cowpox virus
Strain Brighton
Applications
Vaccination recommended for lab staff manipulating vaccinia, monkeypox, or cowpox viruses (CDC/NIH Biosafety in Microbiological and Biomedical Laboratories, 4th ed, 1999 - stock no.
Biosafety Level 2
Isolation
Lesions on hands of milker, England, 1937
Product Format frozen
Storage Conditions Store at -70°C or colder
Genome Sequenced Strain

Yes

Comments
Handle as potentially biohazardous material under Biosafety Level 2+ containment.
Virus characteristics are essentially the same as vaccinia.
REFERENCE STRAIN: Fenner, F. et al., Virology 4: 305, 1957.
GENBANK AF043237, Cowpox virus natural killer cell receptor gene, complete cds.
GENBANK X75158, Cowpox virus gene for 14kDa fusion protein
Vaccination recommended for lab staff manipulating vaccinia, monkeypox, or cowpox viruses (CDC/NIH Biosafety in Microbiological and Biomedical Laboratories, 4th ed, 1999 - stock no. 017-040-00547-4).
Essentially same as vaccinia.
Effect on Host
Yes, in vivo effects: Localized hemorrhagic lesion at inoculation site
Recommended Host
rabbit, i. d. inoculation; primary rabbit kidney cells

Recommended Host:  BS-C-1 (ATCC® CCL-26™ )

rabbit; chicken embryo (chorioallantoic membrane); chicken embryo cells
Growth Conditions
Duration: 2-3 days
Effect on Host
Yes, in vivo effects: Localized hemorrhagic lesion at inoculation site
Name of Depositor AW Downie
Source
Lesions on hands of milker, England, 1937
Year of Origin 1937
References

Davies JH. . Lancet 235: 1534, 1938.

Downie AW. . Br. J. Exp. Pathol. 20: 158, 1939.

Cross References

Nucleotide (GenBank) : X75158 Cowpox virus gene for 14kDa fusion protein

Nucleotide (GenBank) : AF043237 Cowpox virus natural killer cell receptor gene, complete cds.