|
Comments
|
A recombinant virus which produces SV-40 large T antigen and contains a human alphabeta choriogonadotropin clone. This encodes both the alpha and beta subunits of human luteinizing hormone and produces both subunits in host mammalian cells in a biologically active, glycosylated heterodimeric form. The vector is an SV40 deriv with SV40 promoter and pMB1 and SV40 replicons. The LHA gene is on a HindIII fragment. The LHB gene is on an EcoRI/BamHI fragment.
|
|
Effect on Host
|
Cytopathic effects in tissue culture
|