Human adenovirus 18 (ATCC® VR-19)

Classification: Adenoviridae, Mastadenovirus, Human adenovirus A  /  Product Format: frozen

Classification Adenoviridae, Mastadenovirus, Human adenovirus A
Agent Human adenovirus 18
Strain D.C.
Applications
Produces subcutaneous tumors at the site of inoculation in newborn hamsters.
Respiratory research
Biosafety Level 2
Isolation
Anal swab from child with Niemann-Pick syndrome, Washington, DC, 1954
Product Format frozen
Storage Conditions -60°C or colder
Comments
HA activity has not been demonstrated. May require large inocula before satisfactory titers are obtained. Produces subcutaneous tumors at the site of inoculation in newborn hamsters.
REFERENCE STRAIN: Pereira, H.G. et al., Virology 20: 613, 1963.
Effect on Host
Yes, in vitro effects: Cytopathic effects in tissue culture
CPE
Recommended Host
human embryonic kidney cells; HeLa cells (ATCC CCL-2); KB cells (ATCC CCL-17)

Host of Choice:  HEK, HeLa, KB cells

Host Range:  HEK, HeLa, KB and other human cell lines.

Growth Conditions
Duration: 2-3 days
Effect on Host
Yes, in vitro effects: Cytopathic effects in tissue culture
CPE
Name of Depositor M Schaeffer, DA Stevens
Source
Anal swab from child with Niemann-Pick syndrome, Washington, DC, 1954
Year of Origin 1954
References

Hartley JW, et al. Additional serotypes of the APC virus group. Proc. Soc. Exp. Biol. Med. 91: 260-262, 1956. PubMed: 13297771

Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904