cosAChT9/subE4a (ATCC® 65923)

Organism: Homo sapiens, human  /  Clone Type: Clone  / 

Permits and Restrictions

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Designations cosAChT9/subE4a
Species Homo sapiens, human
Construct size (kb): 8.0
DNA: genomic
Insert lengths(kb): 5.0
Gene product: alpha-1-antichymotrypsin [AACT]
Insert Size (kb) 5.0
Biosafety Level 1
Shipping Information Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Restriction digests of the clone give the following sizes (kb): EcoRI--4.9, 3.1; HindIII--8.0; BamHI--4.1, 3.7; PstI--3.4, 2.6, 1.1, 0.68; PvuII--3.2, 2.6, 0.68, 0.56, 0.47, 0.28.
Restriction digests of the plasmid give the following sizes (kb): EcoRI--5.0, 2.96; HindIII--8.0; BamHI--4.9, 3.0; PstI--3.6, 2.6, 1.0, 0.6; SspI--3.9 (doublet).
Contains exon 3 and portions of the flanking introns.

Poller W, et al. Cloning of the human alpha2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site. Hum. Genet. 88: 313-319, 1992. PubMed: 1370808

Faber JP, et al. The molecular basis of alpha 1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J. Hepatol. 18: 313-321, 1993. PubMed: 8228125

et al., et al. . Am. J. Hum. Genet. 49: 134, 1991.

Wolfgang Poller, personal communication

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