cosAChT9/subE4a (ATCC® 65923)

Organism: Homo sapiens, human  /  Clone Type: Clone  / 

Permits and Restrictions

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Designations cosAChT9/subE4a
Species Homo sapiens, human
Vector
Construct size (kb): 8.0
Insert
DNA: genomic
Insert lengths(kb): 5.0
Gene product: alpha-1-antichymotrypsin [AACT]
Insert Size (kb) 5.0
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Comments
Restriction digests of the clone give the following sizes (kb): EcoRI--4.9, 3.1; HindIII--8.0; BamHI--4.1, 3.7; PstI--3.4, 2.6, 1.1, 0.68; PvuII--3.2, 2.6, 0.68, 0.56, 0.47, 0.28.
Restriction digests of the plasmid give the following sizes (kb): EcoRI--5.0, 2.96; HindIII--8.0; BamHI--4.9, 3.0; PstI--3.6, 2.6, 1.0, 0.6; SspI--3.9 (doublet).
Contains exon 3 and portions of the flanking introns.
References

Poller W, et al. Cloning of the human alpha2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site. Hum. Genet. 88: 313-319, 1992. PubMed: 1370808

Faber JP, et al. The molecular basis of alpha 1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J. Hepatol. 18: 313-321, 1993. PubMed: 8228125

et al., et al. . Am. J. Hum. Genet. 49: 134, 1991.

Wolfgang Poller, personal communication

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