p105-599Ha [L599H-a] (ATCC® 59305)

Organism: Homo sapiens, human  /  Clone Type: Clone  / 

Permits and Restrictions
Designations p105-599Ha [L599H-a]
Species Homo sapiens, human
Vector
Construct size (kb): 7.5
Insert
DNA: genomic
Insert lengths(kb): 4.900000095367432
Gene product: DNA Segment, single copy [D5S76]
Alleles: A1, A2, A3
Insert Size (kb) 4.900
Biosafety Level 1
Shipping Information Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug)
Comments
Restriction digests of the clone give the following sizes (kb): EcoRI--6.3, 1.4; HindIII--5.0, 2.7; PstI--4.9, 2.2, 0.4.
Maps between pJO110HC (D5S21) and p105-153Ra (D5S39) with a recombination frequency of 0.10 and 0.12, respectively, in males, and 0.19 and 0.18, respectively, in females.
Contains repetitive elements. Must be competitively hybridized with genomic DNA to reveal the RFLP.
References

Sherrington R, et al. Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature 336: 164-167, 1988. PubMed: 2903449

Kennedy JL, et al. Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree. Nature 336: 167-169, 1988. PubMed: 2903450

McGuffin P, et al. Exclusion of a schizophrenia susceptibility gene from the chromosome 5q11-q13 region: new data and a reanalysis of prevous reports. Am. J. Hum. Genet. 47: 524-535, 1990. PubMed: 2393025

Gilliam TC, et al. Deletion mapping of DNA markers to a region of chromosome 5 that cosegregates with schizophrenia. Genomics 5: 940-944, 1989. PubMed: 2591972

Weiffenbach B, et al. A genetic linkage map of human chromosome 5 with 60 RFLP loci. Genomics 10: 173-185, 1991. PubMed: 1675192

Leppert M, et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 238: 1411-1413, 1987. PubMed: 3479843

Kenneth K Kidd, personal communication

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