Paracoccidioides brasiliensis (Splendore) Almeida, anamorph (ATCC® MYA-826)

Strain Designations: Pb01 [01]  /  Product Format: frozen

Permits and Restrictions

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Strain Designations Pb01 [01]
RAPD analysis
Biomedical Research and Development Material
Biosafety Level 2

Biosafety  classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain no
Preceptrol® no
Genome Sequenced Strain


highly virulent
differential expression of proteins PbY20 (by yeast form) and PbM46 (by mycelial form)
protein synthesis patterns
effect of amphotericin B
expression of gp43
differential expression of gene for heat shock protein, Hsp70
RAPD analysis
Genome sequencing strain (University of Brasil, Brasil).
Medium ATCC® Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions
Temperature: 37.0°C
Name of Depositor CM Soares
Special Collection NCRR Contract
Chain of Custody
ATCC <<--CM Soares<<--M.R.R. Silva 01
clinical isolate, Goiania, Brazil
Cross References

Nucleotide (GenBank) : AF148715 glucan synthase (FKS) gene, complete coding sequence

Nucleotide (GenBank) : U91560 heat shock protein 70 gene, hsp70, complete coding sequence

Complete Genome (GenBank) : ABKH00000000 Paracoccidioides brasiliensis Pb01, whole genome shotgun sequencing project


Pereira M, et al. Molecular cloning and characterization of a glucan synthase gene from the human pathogenic fungus Paracoccidioides brasiliensis. Yeast 16: 451-462, 2000. PubMed: 10705373

Cunha AF, et al. Identification, N-terminal region sequencing and similarity analysis of differentially expressed proteins in Paracoccidioides brasiliensis. Med. Mycol. 37: 115-121, 1999. PubMed: 10361267

Molinari-Madlum EE, et al. Virulence of Paracoccidioides brasiliensis isolates can be correlated to groups defined by random amplified polymorphic DNA analysis. Med. Mycol. 37: 269-276, 1999. PubMed: 10421862

Salem-Izacc SM, et al. Protein synthesis patterns of Paracoccidioides brasiliensis isolates in stage-specific forms and during cellular differentiation. J. Med. Vet. Mycol. 35: 205-211, 1997.

Soares CM, et al. Characterization of Paracoccidioides brasiliensis isloates by random amplified polymorphic DNA analysis. J. Clin. Microbiol. 33: 505-507, 1995. PubMed: 7714219

Jesuino RS, et al. In vitro amphotericin B effects on growth, viability and dimorphism of Paracoccidioides brasiliensis: reversal of the treatment. Microbiol. Immunol. 41: 93-99, 1997. PubMed: 9087951

Mattar-Filho R, et al. Expression of glycoprotein gp43 in stage-specific forms and during dimorphic differentiation of Paraccidioides brasiliensis. J. Med. Vet. Mycol. 35: 341-345, 1997.

da Silva SP, et al. Phase transition and stage-specific protein synthesis in the dimorphic fungus Paracoccidioides brasiliensis. Exp. Mycol. 18: 294-299, 1994.

da Silva SP, et al. Differential expression of an hsp70 gene during transition from the mycelial to the infective yeast form of the human pathogenic fungus Paracoccidioides brasiliensis. Mol. Microbiol. 31: 1039-1050, 1999. PubMed: 10096073

Celia M Soares, personal communication

Wang H, et al. A fungal phylogeny based on 82 complete genomes using the composition vector method. BMC Evol. Biol. 9: 195, 2009. PubMed: 19664262

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation