Streptomyces argillaceus Routien (ATCC® 12956)

Strain Designations: 5576-27  /  Type Strain: no  /  Biosafety Level: 1

Permits And Restrictions

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Strain Designations 5576-27
Produces plicamycin mithramycin
Production of the tumor-inhibiting agents mithramycin A, B and/or C
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Preceptrol® no
Type Strain no
Medium ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor Chas. Pfizer & Co., Inc.
U.S. Patent Number
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished.

Sobin BA, et al. Mithramycins as transplanted tumor inhibiting agents. US Patent 3,646,194 dated Feb 29 1972

Cross References

Nucleotide (GenBank) : Y10907 S.argillaceus mtmD and mtmE genes.

Nucleotide (GenBank) : AJ007932 Streptomyces argillaceus mithramycin biosynthetic genes.

Nucleotide (GenBank) : X89899 S.argillaceus DNA for mtmQ, mtmX, mtmP, mtmK, mtmS and mtmT1 genes.

Nucleotide (GenBank) : AF056309 Streptomyces argillaceus membrane protein and mithramycin regulator MtmR (mtmR) genes, complete cds.

Nucleotide (GenBank) : AF056310 Streptomyces argillaceus sequence similar to the region upstream of the mithramycin regulatory gene.

Nucleotide (GenBank) : U43537 Streptomyces argillaceus mithramycin resistance determinant, ATP-binding protein (mtrA) and membrane protein (mtrB) genes, complete cds.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation