Aspergillus niger van Tieghem, anamorph (ATCC® 9142)

Strain Designations: NRRL 599 [Doelger 2, IMI 41874, X-172]  /  Product Format: freeze-dried

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Strain Designations NRRL 599 [Doelger 2, IMI 41874, X-172]
degrades acronine acronycine
degrades apple pomace
degrades brewery wastes
degrades cotton wastes
degrades inulin
degrades molasses
degrades pineapple wastes
produces 12-hydroxy-trans-nerolidol
produces 18-homo-19-norcortisone
produces 18-homo-19-norhydrocortisone
produces 9-hydroxyacronycine
produces L-malic acid
produces citric acid citrate
produces gluconic acid
produces grindelane dimers
produces hydroxygrindelanes
produces hydroxylated biphenyl compounds
produces hydroxylated steroids steroids, hydroxylated
produces lipase
reduces 3,5-dimethoxycinnamic acid
reduces 3-methobenzoic acid
reduces 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14,17-dione
transforms acronine acronycine
transforms chromanone
transforms flavonoids
Biosafety Level 1
Product Format freeze-dried
Type Strain no
Preceptrol® no
Medium ATCC® Medium 336: Potato dextrose agar (PDA)
Growth Conditions
Temperature: 24.0°C
Sequenced Data
       The ITS DNA sequence of MYA-9142 lot 58090538


Name of Depositor NRRL
Chain of Custody
ATCC <<--NRRL<<--A.J. Moyer strain Doelger 2

Bercovitz A, et al. Localization of pyruvate carboxylase in organic acid-producing Aspergillus strains. Appl. Environ. Microbiol. 56: 1594-1597, 1990. PubMed: 2383004

Schwartz RD. Microbial production of hydroxylated biphenyl compounds. US Patent 4,153,509 dated May 8 1979

Gadsby B, Greenspan G. C-21 hydroxylation products of steroids. US Patent 3,529,000 dated Sep 15 1970

Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971

Arfmann HA, Abraham WR. Microbial reduction of aromatic carboxylic acids. Z. Naturforsch. Sect. C Biosci. 48: 52-57, 1993.

. . J. Chem. Soc. Chem. Commun. 1195: 1157, 1971.

Roukas T. Production of citric acid from beet molasses by immobilized cells of Aspergillus niger. J. Food Sci. 56: 878-880, 1991.

Drysdale CR, McKay AM. Citric acid production by Aspergillus niger in surface culture on inulin. Lett. Appl. Microbiol. 20: 252-254, 1995. PubMed: 7766122

Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of chromone, chromanone, and ring A hydroxyflavones. J. Nat. Prod. 53: 1471-1478, 1990. PubMed: 2089118

Tran CT, et al. Selection of a strain of Aspergillus for the production of citric acid from pineapple waste in solid-state fermentation. World J. Microbiol. Biotechnol. 14: 399-404, 1998.

Heinrich M, Rehm HJ. Formation of gluconic acid at low pH-values by free and immobilized Aspergillus niger during citric acid fermentation. Eur. J. Appl. Microbiol. Biotechnol. 15: 88-92, 1982.

Doelger WP, Prescott SC. Citric acid fermentation. Ind. Eng. Chem. 26: 1142-1149, 1934.

Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940

Hang YD, Woodams EE. Apple pomace: a potential substrate for citric acid production by Aspergillus niger. Biotechnol. Lett. 6: 763-764, 1984.

Roukas T, Kotzekidon P. Production of citric acid from brewery wastes by surface fermentation using Aspergillus niger. J. Food Sci. 51: 225-228, 1986.

Hoffmann JJ, et al. Hydroxygrindelane derivatives by microbial transformation. Phytochemistry 27: 2125-2127, 1988.

Arfmann HA, et al. Microbial omega-hydroxylation of trans-nerolidol and structurally related sesquiterpenoids. Biocatalysis 2: 59-67, 1988.

Roukas T, Alichanidis E. Citric acid production from beet molasses by cell cycle of Aspergillus niger. J. Ind. Microbiol. 7: 71-74, 1991.

Hoffmann JJ, et al. Formation of grindelane dimers by microbial transformation. Phytochemistry 31: 3045-3049, 1992.

Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of (+/-)-flavanone and (+/-)-isoflavanone. J. Nat. Prod. 53: 644-656, 1990. PubMed: 2213034

Miura S, et al. Prostaglandin chemistry -- IV. Microbiological kinetic resolution and asymmetric hydrolysis of 3,5-diacetoxycyclopent-1-ene. Tetrahedron 32: 1893-1898, 1976.

Kiel H, et al. Citric acid fermentation by Aspergillus niger on low sugar concentrations and cotton waste. Appl. Environ. Microbiol. 42: 1-4, 1981.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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