Aspergillus ochraceus Wilhelm, anamorph (ATCC® 18500)

Strain Designations: NRRL 405 [4718]  /  Product Format: freeze-dried

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Strain Designations NRRL 405 [4718]
hydroxylates 11,13-dehydrosantonin
oxidizes chrysanthemol
produces 11-alpha-hydroxyprogesterone
produces L-malic acid
produces Reichstein's compound S
produces succinic acid
transforms flavonoids
oxidizes chrysanthemols to chrysanthemic acids
transformation of: sesquiterpene lactone costunolide
Biosafety Level 1
Product Format freeze-dried
Type Strain no
Preceptrol® no
Medium ATCC® Medium 312: Czapek's agar
Growth Conditions
Temperature: 24.0°C
Name of Depositor NRRL
Chain of Custody
ATCC <<--NRRL<<--C. Thom 4718
rubber sheet

Singh K, et al. Large-scale transformation of steroids by fungal spores. Appl. Microbiol. 16: 393-400, 1968. PubMed: 5645421

Sehgal SN, et al. 11 alpha-hydroxylation of steroids by spores of Aspergillus ochraceus. Can. J. Microbiol. 14: 529-532, 1968. PubMed: 5665975

Miski M, Davis PJ. Microbiologically catalyzed enantio- and diastereoselective oxidation of chrysanthemol stereoisomers to chrysanthemic acids. Appl. Environ. Microbiol. 54: 2268-2272, 1988.

Bercovitz A, et al. Localization of pyruvate carboxylase in organic acid-producing Aspergillus strains. Appl. Environ. Microbiol. 56: 1594-1597, 1990. PubMed: 2383004

Iida M, et al. Microbial hydroxylation of 11,13-dehydrosantonin by Aspergillus niger. J. Ferment. Bioeng. 76: 296-299, 1993.

Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of flavone and isoflavone. Xenobiotica 20: 363-373, 1990. PubMed: 2346033

Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.

Madyastha KM, et al. Studies on the microsomal 11alpha-hydroxylation of progesterone in Aspergillus ochraceus: isolation, characterization, and solubilization of the hydroxylase system. Can. J. Biochem. Cell Biol. 62: 100-107, 1984.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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