Unidentified bacterium (ATCC® 53828)

Strain Designations: MA6474  /  Type Strain: no  /  Biosafety Level: 1

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Deposited As Unidentified actinomycete
Strain Designations MA6474
Application
Produces immunosuppressant L-685,487 L-685,487
Isolation
Soil
Type Strain no
Biosafety Level 1
Product Format freeze-dried
Preceptrol® no
Type Strain no
Comments
Bioconversion of Simvastatin
Medium ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor Merck & Co., Inc.
Isolation
Soil
References

Arison BH, et al. Microbial transformation product of L-683,990. US Patent 4,975,372 dated Dec 4 1990

Marcin C, et al. Bioconversion of the sodium salt of simvastatin (MK-733) to 6-desmethyl- 6-alpha-hydroxymethyl simvastatin. J. Ind. Microbiol. 8: 157-164, 1991. PubMed: 1367898

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation