Dengue virus type 4 (ATCC® VR-1726)

Classification: Flaviviridae, Flavivirus  /  Product Format: frozen
Approximately 100 µL of purified monoclonal antibody in PBS

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Classification Flaviviridae, Flavivirus
Agent Dengue virus type 4
Strain Monoclonal Anti-Dengue virus type 4 E protein, clone E62 (produced in vitro)
Applications
Emerging infectious disease research
Biosafety Level 1
Product Format frozen
Approximately 100 µL of purified monoclonal antibody in PBS
Storage Conditions  -20°C or colder Repeated freeze-thaw cycles should be avoided
Comments
Antibody Class: IgG2aκ
The B cell hybridoma was generated by the fusion of P3X63.Ag.8.6.5.3 BALB/c mouse myeloma cells with immunized mouse splenocytes.
Name of Depositor MS Diamond, Washington University in St. Louis, School of Medicine
Source
Mouse monoclonal antibody prepared against the envelope glycoprotein of dengue virus type 4 was purified from clone E62 hybridoma supernatant by protein G affinity chromatography.
References

Balsitis SJ, et al. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6: e1000790, 2012. PubMed: 20168989

Rajamanonmari R, et al. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J. Gen. Virol. 90: 799-809, 2009. PubMed: 19264660

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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