Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow (ATCC® 31267)

Strain Designations: NRRL 8165 [JCM 5070, MA-4680, NCIMB 12804]  /  Type Strain: yes  /  Biosafety Level: 1

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These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Deposited As Streptomyces avermitilis
Strain Designations NRRL 8165 [JCM 5070, MA-4680, NCIMB 12804] (genome sequencing strain), RefIkeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562
Application
Produces avermectin avermectins
Produces avermectin B(1)a C-076
Produces C-076 and derivatives
Isolation
Soil, Ito City, Shizuoka Pref., Japan
Type Strain yes RefKim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861
Biosafety Level 1
Product Format freeze-dried
Genome Sequenced Strain

Streptomyces avermitilis MA-4680 DNA, complete genome.

Type Strain yes RefKim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861
Comments
Genome sequenced strain
Medium ATCC® Medium 184: Glucose asparagine agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor NRRL
Special Collection NSF - Bacteriology
Chain of Custody
ATCC <<--NRRL<<--Merck & Co., Inc. MA-4680
Isolation
Soil, Ito City, Shizuoka Pref., Japan
References

Burg RW, et al. Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation. Antimicrob. Agents Chemother. 15: 361-367, 1979. PubMed: 464561

Miller TW, et al. Avermectins, new family of potent anthelmintic agents: Isolation and chromatographic properties. Antimicrob. Agents Chemother. 15: 368-371, 1979. PubMed: 464562

Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983

Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996

Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983

genome sequencing strain

Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562

Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861

genome sequencing strain

Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562

Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861

Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861

Cross References

Nucleotide (GenBank) : AY029771 Streptomyces avermitilis ribosomal protein S12 (rpsL) gene, complete cds.

Nucleotide (GenBank) : BA000030 Streptomyces avermitilis MA-4680 DNA, complete genome.

Permits Notice: Necessary Permits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation