Breast Cancer p53 Hotspot Mutation Cell Panel (ATCC® TCP-2010)

Organism: Homo sapiens, human  / 

Organism Homo sapiens, human
Components
MDA-MB-175-VII, ATCC HTB-25
MDA-MB-361, ATCC HTB-27
AU565, ATCC CRL-2351
SK-BR-3, ATCC HTB-30
HCC70, ATCC CRL-2315
BT-549, ATCC HTB-122
HCC38, ATCC CRL-2314
MDA-MB-468, ATCC HTB-132
Applications
Biological understanding of top genetic alterations across tumor types
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Type Strain no
Biosafety Level 1
Comments
The Breast Cancer p53 Hotspot Mutation Cell Panel is comprised of 8 select cell lines derived from breast cancer that have been sequenced and validated by ATCC. The panel includes both WT p53 cell lines as well as cultures with p53 hotspot mutations at codons 175, 248, 249, or 273.
Product Format frozen
Storage Conditions LN vapor (less than -130°C) only