PTEN Genetic Alteration Cell Panel (ATCC® TCP-1030)

Organism: Homo sapiens, human  / 

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Organism Homo sapiens, human
Components ATCC CRL-1718 CCF-STTG1
ATCC HTB-111 AN3 CA
ATCC HTB-31 C-33-A
ATCC HTB-66 RPMI-7951
ATCC HTB-148 H4
ATCC HTB-12 SW 1088
ATCC CRL-1585 C32
ATCC CRL-1620 A172
ATCC HTB-1 J82
ATCC CRL-11730 TOV-21G
Applications This panel is useful for PTEN pathway and PI3K pathway research and for anti-cancer drug discovery.
Biosafety Level 1
Comments

PTEN is a tumor suppressor gene that encodes for a lipid phosphatase protein that down-regulates PI3K activity, which in turn affects the AKT signaling pathway and regulation of the cell cycle. Mutations in this gene are associated with a variety of cancers, including brain, skin and ovarian.

The PTEN genetic alteration cell panel (ATCC TCP-1030) is composed of ten human tumor cell lines from common cancer types that carry PTEN mutations or PTEN deletions. The PTEN status of each cell line has been sequenced and validated by ATCC. This panel is useful for PTEN and PI3K pathway research and for anti-cancer drug discovery.

Product Format frozen
Storage Conditions LN vapor (less than -130°C) only
Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation
Other Documentation
FAQs
  1. Tumor Cell Panels


    Date Updated: 3/27/2014

  2. Molecular Signature Panels

    Date Updated: 3/27/2014
  3. Tumor cell panels by tissue type


    Date Updated: 3/27/2014

  4. Tumor cell panels by tissue type vs. molecular signature


    Date Updated: 3/27/2014

  5. Validated genetic information for tumor cell panels
    It depends on the types of panels. There are mainly two kinds ...
    Date Updated: 3/27/2014
  6. Control cell line for tumor cell panels


    Date Updated: 3/27/2014

  7. Nucleic acids and cell pellets for ATCC Cell Panels


    Date Updated: 3/27/2014

  8. Gene mutation information for molecular signature panels


    Date Updated: 3/27/2014