Human adenovirus 2 (ATCC® VR-846)

Classification: Adenoviridae, Mastadenovirus, Human adenovirus C  /  Product Format: frozen 1 mL per vial

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Classification Adenoviridae, Mastadenovirus, Human adenovirus C
Deposited As Adenovirus type 2
Agent Human adenovirus 2
Strain Adenoid 6
Testing disinfectants
Testing virucides
This strain is recommended by ATCC for use in the tests described in Federal Specifications A-A-1438, A-A-1439, A-A-1440, A-A-1441, and A-A-1443 where only the taxon is specified.
Respiratory research
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen 1 mL per vial
Storage Conditions -70°C or colder

This strain is incorrectly listed in ASTM Standard Test Methods E1052-85 and E1053-91 as VR-2.

Recognized Reference Strain: Pereira, H.G. et al., Virology 20:613, 1963. Agglutinates rat RBC (incompletely). Derived from passage of VR-1079 (NIAID V-202-001-014) at ATCC.

Effect on Host
CPE, refractile rounding and sloughing
Recommended Host
MRC-5 (ATCC® CCL-171™)
Growth Conditions Temperature: 37°C
Recommendations for Infection: For best results cells should be 24 to 48 hours old and 80-90% confluent (not 100% confluent).
Incubation: 2-3 days, a 5% CO2 in air atmosphere is recommended
Effect on Host
CPE, refractile rounding and sloughing
Name of Depositor NIH/NIAID
Special Collection ATCC
Source Spontaneously degenerating tissue culture of adenoid tissue from 7-year-old girl with hypertrophied tonsils and adenoids, Washington, DC, 1953.

Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904

Huebner RJ, et al. Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc. Soc. Exp. Biol. Med. 84: 570-573, 1953. PubMed: 13134217

Huang S, et al. Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells. J. Virol. 70: 4502-4508, 1996. PubMed: 8676475

Rowe WP, et al. Studies of the adenoidal-pharyngeal-conjunctival (APC) group of viruses. Am. J. Hyg. 61: 197-218, 1955.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation