Monoclonal Anti-Dengue virus type 4 envelope protein, Clone E40 (produced in vitro) (ATCC® VR-1722™)

Classification: Flaviviridae, Flavivrus  /  Product Format: frozen

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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Classification Flaviviridae, Flavivrus
Agent Monoclonal Anti-Dengue virus type 4 envelope protein, Clone E40 (produced in vitro)
Biosafety Level 1
Product Format frozen
Storage Conditions -20°C or colder. Repeated freeze-thaw cycles should be avoided.
Comments Antibody Class: IgG2aκ
The B cell hybridoma was generated by the fusion of P3X63.Ag.8.6.5.3 BALB/c mouse myeloma cells with immunized mouse splenocytes.
Name of Depositor MS Diamond, Washington University in St. Louis, School of Medicine
Source Mouse monoclonal antibody prepared against the envelope glycoprotein of Dengue virus type 4 (DEN-4) was purified from clone E40 hybridoma supernatant by protein G affinity chromatography.
References

Balsitis SJ, et al. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6: e1000790, 2012. PubMed: 20168989

Rajamanonmari R, et al. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J. Gen. Virol. 90: 799-809, 2009. PubMed: 19264660

Permits Notice: Necessary Permits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation
Product Sheet
Product Sheet
Certificate of Analysis
Certificate of Analysis
MSDS
MSDS