Lymphoma p53 Hotspot Mutation Cell Panel (ATCC® TCP-2050)

Organism: Homo sapiens, human  / 

Organism Homo sapiens, human
Components EB-3,  ATCC CCL-85
CA46,  ATCC CRL-1648
Namalwa,  ATCC CRL-1432
DB,  ATCC CRL-2289
SUP-T1,  ATCC CRL-1942
Applications Biological understanding of top genetic alterations in lymphoma
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Biosafety Level 2   [Cells contain herpes virus]
Comments

The Lymphoma p53 Hotspot Mutation Cell Panel is comprised of five select suspension cell lines derived from lymphomas. Mutations have been sequenced and validated by ATCC. This panel includes a cell line with WT p53 as well as cell lines with p53 hotspot mutations at codons 248 and 273

Product Format 5 cryopreserved cell lines
Storage Conditions liquid nitrogen vapor phase