2013 Excellence in Research Series
ATCC, your trusted source for cell lines, microbial strains, and other biological reagents, invites you to view one of the exciting webinars in our 2012 Excellence in Research series. Each webinar featured a highly experienced ATCC Scientist who demonstrated how to utilize ATCC products and services to advance your research. The webinars were broadcasted live, ran 30 to 45 minutes, and were followed by a 10 minute question and answer period.

Tumor Cell Panels in Cancer Research and Drug Discovery
Fang Tian, Senior Scientist, Cell Biology
Thursday, August, 23rd 1:00 pm (EST)
Human cancer cell lines have been used as essential tools in both high-throughput drug screening and detailed molecular mechanism studies. This Webinar will focus on genetic characterization of human cancer cell lines currently used in laboratories. Additionally, it will introduce how to choose the best cell lines and cell line panels for biological understanding of top genetic alterations across tumor types, and for testing small molecules or biologics for cancer drug development. View Recording

Biological Resources of the ATCC Protistology Collection
Robert Molestina, PhD, Senior Scientist
Thursday, September 6th 1:00 pm (EST)
Protists are eukaryotic microorganisms commonly studied due to their ecological relevance in aquatic food chains and their impact on human health. Protistology research and comparative studies are dependent on the accessibility of authenticated biological standards. To meet this need, the Protistology Collection at the ATCC houses the largest and most diverse repository of protist cultures in the world. The primary role of the collection has been the acquisition, authentication, preservation, and distribution of reference strains. Characterization of deposited cultures includes a variety of tests such as viability, purity, phenotypic properties, and genotypic analysis. Additionally, over the last decade, resources within the collection have expanded to include genomic DNA and custom services. This presentation will provide an overview of biological resources available in the ATCC Protistology Collection, a discussion on the methods of characterization, benefits of depositing, current research projects, and future perspectives. View Recording

Stem Cell Solutions
Yukari Tokuyama, Scientist
Thursday, September 20th 1:00 pm (EST)
This webinar will introduce ATCC’s stem cell products, which includes human induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), human mesenchymal stem cells (MSCs) and mouse ESCs. The focus will be on hurdles currently facing human iPSCs culture systems and we will introduce ATCC® Complete Stem Cell Solution™, which provides researchers with reliable, authenticated cells and optimized media and reagents in a single easy to use system. Download Q&A session (.pdf). View Recording


Assessing Novel Storage Techniques and Their Ability to Stabilize Nucleic Acids
Kurt Langenbach, PhD, Manager, Research Scientist, Cores and
Maria Mayda, Scientist, Assay Development
Thursday, October 4th 1:00 pm (EST)
Novel ambient temperature stable storage approaches offer the potential advantage that various materials, such as nucleic acids, could be subjected to a broad range of hostile temperatures without diminishing and perhaps even improving their performance in downstream applications. In this webinar, we will discuss some of the results generated through our technology assessment program that have focused on evaluating innovative methods for the collection, processing, preservation, and characterization of bio-specimens, including nucleic acids, at ambient temperature. Insights gathered from these studies will allow us to move beyond traditional biological sample storage concepts, enhance the quality and reproducibility of results, improve sample handling, and minimize the impact of deleterious events in cold chain management. Download Q&A session (.pdf). View Recording


Updates to the ATCC Material Transfer and Deposit Agreement: How ATCC Helps You in Research
Stewart Davis, CLP, RTTP, Director, Intellectual Property & Licensing and
Emily Williams, Technology Licensing Specialist
Thursday, October 18th 1:00 pm (EST)
Earlier this year, ATCC revised its Material Transfer Agreement, to enable researchers and external research sites to transfer key biological reagents derived from ATCC material, such as transfected cell lines and genomic DNA, to collaborators without seeking permission from ATCC or paying administrative transfer fees. Additionally, the ATCC Deposit Agreement has been updated to allow those depositing with ATCC to share in the financial success of a deposit by receiving a royalty stream, once a certain sales threshold has been reached. In this webinar, we will provide more details about these updated agreements, and address how these changes affect the research community. Download Q&A session (.pdf). View Recording

hTERT-Immortalized Cells - Unique Tools for Tissue-Relevant Research
CK Zhang, Scientist, ATCC Cell Systems
Thursday, November 1st 1:00 pm (EST)
ATCC hTERT immortalized cell lines represent a breakthrough in cell biology research that combines the in vivo nature of primary cells and the in vitro utility of continuous cell lines. Normal primary cells are difficult to isolate, often vary from lot to lot, and senesce after a few passages. Traditional cell lines, on the other hand, are genetically unstable and present inconsistent phenotypes over time. In this webinar, we are going to use an hTERT-immortalized Renal Proximal Tubular Epithelial Cell line (RPTEC/TERT1, CRL-4031) as an example to show how cell biologists can use the hTERT cell lines from ATCC as valuable tools for the studies of cell functions in vitro. Download Q&A session (.pdf). View Recording

Non-O157 Shiga Toxin-Producing Escherichia coli
Brian Beck, PhD, Manager, Research Scientist, Microbiology
Thursday, November 15th 1:00 pm (EST)
The global community has been experiencing food-associated outbreaks of non-O157 Shiga toxin-producing Escherichia coli (STEC) for nearly two decades. As a result, six non-O157 STEC strains were classified as adulterants by the Food Safety and Inspection Service branch of the U.S. Department of Agriculture in June 2012, requiring routine verification testing of raw beef manufacturing trimmings for serogroups O26, O45, O103, O111, O121, and O145. ATCC has recently accessioned representative strains (both toxigenic and non-toxigenic) for each serogroup from the CDC and now has them available for use as controls for diagnostics and process validation. This webinar will discuss the genetic and phenotypic methods used to characterize these strains. Download Q&A session (.pdf). View Recording

Cell Line Cross-contamination: Impact on Biomedical Research
Yvonne Reid, PhD, Manager, Scientist, Cell Culture Contracts
Thursday, November 29th 1:00 pm (EST)
The misidentification of human cell lines in research labs is a significant problem that may be costing the scientific community millions of dollars annually. Authenticating human cell lines is a crucial, yet underappreciated, quality control step for researchers performing cell biology, genetic mapping, gene expression, and gene therapy research. View Recording
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