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Bacteria
ATCC® Number: 31267™    Price: $205.00
Organism: Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow deposited as Streptomyces avermitilis
Designations: NRRL 8165 [JCM 5070, MA-4680, NCIMB 12804]
Isolation: soil, Ito City, Shizuoka Pref., Japan
Depositor: NRRL
History: ATCC <<--NRRL<<--Merck & Co., Inc. MA-4680
Biosafety Level: 1
Shipped: freeze-dried
Growth Conditions: ATCC medium184: Glucose asparagine agar
Temperature: 26.0°C
Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Cross References: Nucleotide (GenBank) : BA000030Streptomyces avermitilis MA-4680 DNA, complete genome.
Nucleotide (GenBank) : AY029771 Streptomyces avermitilis ribosomal protein S12 (rpsL) gene, complete cds.
Type Strain: yes [72039]
Comments: Genome sequenced strain
Applications: produces avermectin avermectins [1749] [11214] [1750]
produces avermectin B(1)a C-076 [16587] [3612]
produces C-076 and derivatives [3612] [16587]
Related Products: purified DNA:ATCC 31267D-5
References: 1749: Burg RW, et al. Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation. Antimicrob. Agents Chemother. 15: 361-367, 1979. PubMed: 464561
1750: Miller TW, et al. Avermectins, new family of potent anthelmintic agents: Isolation and chromatographic properties. Antimicrob. Agents Chemother. 15: 368-371, 1979. PubMed: 464562
3612: Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983
11214: Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996
16587: Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983
71399: Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562
72039: Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861
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